Figure 4C and D indicated that tumor cells Cav-1 status had no significant correlation with overall survival and disease free survival (P = 0.178 and 0.104, respectively). Moreover, the cumulative 5 year survival rate of patients whose tumors exhibited high CAFs Cav-1 expression was 75.5% (95% CI, 0.642–0.868), whereas it was only 57.4% (95% CI, 0.456–0.692) in low CAFs Cav-1 group (P = 0.053). Here, CAV1 is linked to neoplasm.