Furthermore, the frequency of IL-22 positive CD4+ T cells from BD patients with active uveitis (2.8%±1.14%) was significantly higher than from BD patients without active uveitis (0.97%±0.44%, p = 0.002) or normal controls (1.23%±0.51%, p = 0.005) (Fig. 2A, 2B). Here, IL22 is linked to uveitis.