The results showed that the frequency of IL-22/IL-17 double positive CD4+T cells from BD patients with active uveitis (0.86%±0.27%) was significantly higher than in BD patients without active uveitis (0.40%±0.13%, p<0.001) or normal controls (0.43%±0.15%, p = 0.001) (Fig. 3A, 3B). Here, CD4 is linked to uveitis.