KLF2 and newborn respiratory distress syndrome: Recently, Pei et al. reported that defective differentiation of alveolar epithelial type I cells led to a respiratory distress syndrome-like phenotype in SMRT mutant mice and that 21 genes, including Klf2, Lgals3bp, Klf4, Inmt, Zfp36, and Dusp1, were significantly decreased [15].