APOE and atherosclerosis: Just as lesion area is a quantitative trait that can be used for gene mapping studies, gene expression levels can likewise be treated as a quantitative trait to map the expression QTLs (eQTLs), or the loci that control the expression of specific transcripts.6 We had previously performed an eQTL analysis using macrophages from the F2 cohort of the AKR apoE−/−×DBA/2 apoE−/− strain intercross.7 Here, we report atherosclerosis (Ath) QTL and eQTL findings from a second independent strain intercross of these same 2 strains.