BMPR2 and pulmonary arterial hypertension: Also, newly investigated microRNA could have a potential role in this signaling pathway, as Dr Hart's team demonstrated the implications of miR17‐92 and miR21 in PPARγ regulation,40 and we also demonstrated that miR‐204 could indirectly, through Src kinase activity, modulate BMPR2 expression.38 Marx et al demonstrated that miR21 was increased in human PAH‐PASMCs and that PPARγ ligands attenuate these microRNA alterations.