AGER and pulmonary arterial hypertension: To investigate the pattern of RAGE expression in normal and PAH lungs, we examined RAGE mRNA levels in total lung and RAGE protein levels in distal PAs from 5 rats with Sugen‐induced PAH compared with 5 control rats (Figures 5A and S3) and from 5 rats with monocrotaline‐induced pulmonary hypertension compared with 5 control littermates (Figures 5A and S4) by qRT‐PCR, immunoblots, and immunofluorescence (≥1.5‐fold increase, n=5 per group, P<0.01).