IGF1 and posterior cortical atrophy: Interestingly, however, a distinct signaling of the synthetic human Ec peptide compared to IGF-I ligand (mature peptide) signaling, previously revealed in myoblast-like cells (Philippou et al., 2009) and myocardial-like cells (Stavropoulou et al., 2009), was demonstrated in PC-3 and LNCaP PCa cells (Armakolas et al., 2010).