Table 2 showed: The frequency of anti-p53 antibodies using a cutoff point of 0.4 OD in viral-associated HCC patients, were positive in 168 of 242 (69.42%), non-B non-C HCC in 26 of 39 (66.66%) and liver cirrhosis in 4 of 20 patients (20%). Here, TP53 is linked to cirrhosis of liver.