TOP2A and hepatocellular carcinoma: The most relevant result is the identification of an HCC-related index consisting of 13 genes (TERT, IGF2, GJB2, TEF, TIAM1, CXCL12, TOP2A, A2M, PLG, ARF, PDGFRA, MKI67, and THBS1), which allowed the diagnosis of HCC with a high sensitivity and a specificity of 100%.