BRCA1 and neoplasm: However, a strong correlation was observed between the mRNA expression levels of APTX and BRCA1 (rho = 0.53, P < 0.001), APTX and ERCC1 (rho = 0.73, P < 0.001), BRCA1 and ERCC1 (rho = 0.48, P < 0.001) in tumor.