Further, SNPs in β-catenin rs4135385 was associated with increased risk (AG genotype; OR, 3.03) and TCF7L2 rs12255372 was associated with decreased risk of breast cancer (TT genotype; OR, 0.213) in older age group patients (>43 years) similar to that observed in the overall study population. This evidence concerns the gene TCF7L2 and breast cancer.