LSD1 took an important part in chromatin remodeling and transcriptional regulation in breast cancer cells [22] including MRMT-1 cancer cell line as well as in many other cancers such as the prostate cancer [6], [11], [18], the bladder carcinomas [6], [19], [20] and the lung cancer [7], [19], [21]. This evidence concerns the gene KDM1A and Familial prostate cancer.