When serum levels of hepatic fibrosis markers were then compared in patients with TE values below or above this threshold, we observed similar results to those obtained from the comparison of patients with and without CFLD as defined by recent guidelines: Endoglin was significantly increased in patients with liver stiffness values above 6.3 kPa whereas PTX3 was again significantly decreased in patients with TE values above 6.3 kPa (Figure 7). This evidence concerns the gene PTX3 and Hepatic fibrosis.