TGFB1 and Hepatic fibrosis: Among these up-regulated proteins, we found several proteins that have been well described in the context of hepatic fibrosis, e.g. such as LAP/TGF-ß1 [31], [32], members of the activin family [33], the plasminogen activator system such as uPA [34], or members of the CX3C chemokine family such as fractalkine [35].