VEGFA and neoplasm: Unfortunately, differential, RAD001 tumor volume diminution had already reached statistical significance by day 7, as determined by one-way ANOVA, p = 0.003 for the day 0-day 7 interval or single time point analysis of day 7 tumor size between the vehicle and RAD001 groups, Mann-Whitney U-test, p = 0.013, preventing determination of the predictive value of VEGF-PET imaging at this time point (Figure 5).