The TFs were found relevant to the previously predicted network components in all subnetworks using the subcohort of 61 group IE (ER(+) and PR(+)) and 91 ER(-) breast cancer patients (152A) but not using the subcohort of 18 and 7 non-tumor samples (NT) from ER(+) and ER(-) patients, respectively (Figure 7B). Here, ESR1 is linked to breast cancer.