The overexpression of SPARC has been documented in several types of solid tumors, such as breast tumors [11], prostate tumors [12], melanomas [13], glioblastomas [14], esophageal tumors [15], lung tumors [16], kidney tumors [17], bladder tumors [18] and liver tumors [19]. The gene discussed is SPARC; the disease is prostate neoplasm.