ARC and Tinnitus: A significant decline of Arc expression in neurons was found in all layers of the AC of animals with tinnitus monitored following both exposure protocols (1 h, 120 dB SPL, 10 kHz, Fig. 4A and C and 1.5 h, 120 dB SPL, 10 kHz, Fig. 4B and C) in comparison to no-tinnitus animals (n = 3 animals, p<0.001 for unpaired Student’s t-test, α = 0.05).