EGFR通过参与NSCLC细胞对放射致死性损伤(DNA double-strand break, DSB)修复而导致放疗抵抗。激活的EGFR主要通过参与非同源末端连接(non homologous end-joining, NHEJ)和同源重组修复(homologous recombination, HR)途径对DNA损伤进行修复[8]。. Here, EGFR is linked to non-small cell lung carcinoma.