Another interesting miRNA, miR-126, is silenced in a variety of common human cancers and suppresses metastatic endothelial-cell recruitment in non-cell-autonomous cancer progression processes through the coordinated targeting of IGFBP2, PITPNC1, and MERTK, which are novel proangiogenic genes and biomarkers of human metastasis [51]. Here, IGFBP2 is linked to cancer.