Also, Kim et al. showed that PEI-g-PEG-1.3RGD/pCMV-sFLT-1 delivery in colon adenocarcinoma cells had no inhibitory effect on the growth of colon adenocarcinoma cells, whereas the transfection of primary endothelial cells (CADMEC) with PEI-g-PEG-1.3RGD/pCMV-sFLT-1 resulted in the suppression of VEGF-driven proliferation of endothelial cells. This evidence concerns the gene VEGFA and colon adenocarcinoma.