On the other hand, other studies which focused on the sFLT-1 gene delivery in solid tumours reported only the inhibitory effect of sFLT-1 on the proliferation of endothelial cells in vitro, while the inhibitory effect of sFLT-1 on the VEGF-mediated proliferation of tumour cells in vitro was not studied [19, 22]. Here, VEGFA is linked to neoplasm.