T. cruzi-infected recipient mice receiving CD4+CD25+ T cells from rSSP4-immunized donors developed significantly less severe cardiac inflammation (+) (Figure 1(a), right panels; Figure 1(c)) but higher heart parasite loads (▸)(Figure 1(a), right panels; Figure 1(b)) and higher blood parasitemia (○) compared to controls (◊) (Figure 1(d)). The gene discussed is CD4; the disease is parasitic infectious disease.