CAD and infection: Moreover, identification of TvLEGU-1 in vaginal washes from women with active trichomoniasis is consistent with the presence of the CP30 proteolytic activity [7] in trichomoniasis symptomatic patients [7, 59], suggesting that, during infection, T. vaginalis releases several CPs, including TvLEGU-1, which is highly immunogenic [15].