NR3C2 and infection: Mannose Receptor (MR). Enzyme binding assays using HRP (horseradish peroxidase) as the mannosylated ligand, which were used to characterize the cardiomyocyte mannose receptor (CM-MR) and its involvement in T. cruzi invasion, demonstrated that after the infection of cardiomyocytes (CM) with T. cruzi, a considerable reduction in HRP binding was noticed.