Immunohistochemical reactions with antibodies against ACTH, PRL, GH, LH, and FSH were performed for comprehensive functional assessment in 46 corticotropinomas and 18 ACTH ectopic tumours (all EAS neoplasms were examined for CRH expression, none of them expressed FSH). Here, BRD2 is linked to ACTH-producing pituitary gland adenoma.