CASQ2 and catecholaminergic polymorphic ventricular tachycardia: This may be related to catecholamine-induced polymorphic ventricular tachycardia (CPVT) in which adrenergic stimulation can frequently cause lethal arrhythmias in mice with CASQ2 loss of function alterations (Song et al., 2007; Terentyev et al., 2008).