Although NEUROG1 and CDKN2A have shown to be methylated in colorectal cancers [45], [46], CSMD1-3 methylation did not correlate with NEUROG1 (p = 0.432, R = .1081) or CDKN2A (p = 0.537, R = .08488) methylation, though these two markers did positively correlate with each other (p<0.01) (Table 3 & Table 4). The gene discussed is CDKN2A; the disease is colorectal cancer.