Figure 5E showed the reduction ratios of relative TER level postinfection: Salmonella-induced reduction ratio of the TER was not significantly different from the cells with normal claudin-2 expression level at 30, 60, 120, and 180 minutes postinfection (Fig.5E). Rather, Salmonella-induced TER change was significantly different at 240 and 300 minutes time points (Fig. 5E). Overall, claudin-2 knockdown cells had higher TER compared to the cells with normal claudin-2 level before and post Salmonella infection. The gene discussed is CLDN2; the disease is Salmonella Infections.