Myeloperoxidase-antineutrophil cytoplasmic antibodies (MPO-ANCAs) have been thought to be related to the pathogenesis of MPO-ANCA-associated glomerulonephritis (GN) by binding to the MPO molecules that appear on the surface of primed neutrophils which causes release of oxygen radicals [1]. This evidence concerns the gene MPO and ganglioneuroma.