Delhaye et al. used in situ hybridization and immunohistochemistry to characterize in vivo IFN-producing cells, after infection with two neurotropic viruses that infect mostly neurons: La Crosse virus (bunyaviridae) and the GDVII neurovirulent strain of Theiler's virus (picornaviridae) [61]. This evidence concerns the gene IFNA1 and infection.