In this article, two kinds of ovarian cancer (OVCAR-3 and CP-70) cell lines and a normal ovarian cell line (IOSE-364) were chosen and treated with baicalin and baicalein at different concentrations to test their inhibitory effects on viability, phosphorylation of Akt, and expression of several genes including VEGF, HIF-1α, cMyc, NFκB, and PTEN. Here, HIF1A is linked to ovarian cancer.