PTPRC and pulmonary arterial hypertension: They also were able to moderate pulmonary hypertension and hypoxemia and, in the case of bone marrow cells and cultured CD45neg, attenuated the increase in serum levels of the pro-inflammatory cytokines TNF-α and IL-1β.Neither autologous buffy coat cells nor hematopoietic CD45 (+) cells had those effects.