TYRO3 and systemic lupus erythematosus: Soluble Tyro3 had the largest increase in concentration, more than double the concentration of the control group (1.65 ± 0.93 ng/mL in controls versus 3.62 ± 1.13 ng/mL in SLE patients), followed by sAxl (1.3-fold increase), and sMerTK (1.2-fold increase).