TLR7 and systemic lupus erythematosus: Significantly higher mean fluorescence intensity (MFI) of TLR7 staining on circulating pre-mDCs and mDCs was also observed in patients with active AOSD (median 7.23, IQR 5.00 to 8.69 and 9.30, IQR 6.85 to 11.35, respectively) and in active SLE (median 6.69, IQR 5.69 to 9.84 and 8.80, IQR 7.08 to 10.35, respectively) than in healthy controls (median 3.47, IQR 2.88 to 4.78 and 4.65, IQR 2.98 to 6.00, respectively) (all P <0.001).