The disease activity scores were positively correlated with the percentages of TLR7-expressing pre-mDCs and mDCs in AOSD patients (r = 0.600 and r = 0.597, respectively, both P <0.005) and SLE patients (r = 0.477 and r = 0.422, respectively, both P <0.05). The gene discussed is TLR7; the disease is systemic lupus erythematosus.