MACC1 and breast cancer: As breast cancer patients with positive lymph nodes (LN+) are far more likely to relapse than those with negative lymph nodes (LN-)[27], in order to investigate the prognostic value of MACC1 in LN- and LN + patients, LN status stratification were employed for further Kaplan-Meier analysis on correlations of RFS with the MACC1 expression level in these two groups.