Macfarlane et al. in a study of lower respiratory tract infections in patients attending an outpatient setting, reported that 65% of patients with radiographically confirmed disease showed high serum CRP levels (above 5 mg/dL) compared with 40% in those with radiographic findings that were consistent with infection, and 11% in those who had no changes consistent with infection [1]. Here, CRP is linked to Recurrent lower respiratory tract infections.