SERPINC1 and Nephropathy: Nephropathy, which has been associated to immune-mediated mechanims, is characterized by presence of membranoproliferative glomerulonephritis and tubulointerstitial nephritis (rarely amyloidosis) [31] that can enable the loss of antithrombin III, a potent inhibitor of serine proteases in the coagulation cascate, contributing to the development of DIC.