Evidence that some SNPs of the DAO, DAOA, PPP3CC, and DTNBP1 alleles contribute to conferring an increased risk of schizophrenia are counterbalanced by others indicating that they do not increase risk or even exert a protective effect (http://www.schizophreniaforum.org/res/sczgene). The gene discussed is DAO; the disease is schizophrenia.