Another group of scientists have used mismatch repair detection (MRD) approach to screen 93 matched tumor-normal sample pairs and 22 cell lines for somatic mutations in 30 cancer relevant genes, and found a total of 152 somatic mutations in breast and colorectal cancers [8], including previously reported genes, such as BRAF and KRAS. The gene discussed is BRAF; the disease is colorectal cancer.