In the EPIC cohort (n = 370 cases), significant positive associations with breast cancer risk were observed for both testosterone (4th vs. 1st quartile OR: 1.7, 95% CI: 1.2 to 2.6, Ptrend = 0.01) and DHEAS (OR = 1.5, 95% CI: 1.0 to 2.1, Ptrend = 0.10) [12]. The gene discussed is SULT2A1; the disease is breast cancer.