Coefficients of univariate and multivariate regression models between independents variables (sex, age ≥ 50 years, apo E2/E3 or apo E4/E3 polymorphism versus apo E3/E3, and T2DM) and dependent variables (BMI ≥ 30, central obesity, high blood pressure, high level of total cholesterol or triglycerides) are shown in Table 3. The gene discussed is AOPEP; the disease is hypertensive disorder.