With the same critia for paracancerous laryngeal epithelium and cancer, immunohistochemical analysis showed that high, medium and low expression levels of PTK6 were 25 of 76 (32.9%), 31 of 76 (40.8%) and 20 of 76 (26.3%), respectively, in the whole paracancerous laryngeal epithelial sample, while high, medium and low expression levels of PTK6 were 39 of 134 (29.1%), 59 of 134 (44.0%) and 36 of 134 (26.9%), respectively, in the whole LSCC cohort. Here, PTK6 is linked to cancer.