TLR3 and chronic obstructive pulmonary disease: When we analyzed smokers with COPD versus smokers without COPD, no significant differences were seen in TLR3 mRNA transcripts (COPD, 0.23 ± 0.16 vs. no COPD, 0.49 ± 0.49, mean ± SEM dRn; p = 0.52, unpaired t test) or flow cytometric results (COPD, 12.2 ± 12.2 vs. non-COPD, 10.4 ± 5.2; mean ± SEM % TLR3-positive AMø, p = 0.87, unpaired t test).