The use of NS1-antigen test identified 18.6% of patients who would have been missed if IgM test alone (without NS1-antigen test) were used to confirm acute dengue, whereas the use of IgM test identified 51.5% of patients who would have been missed if NS1-antigen test alone (without IgM test) were used to confirm acute dengue. Here, CD40LG is linked to dengue disease.