Similarly, in a subgroup of patients screened negative for MDE according to the BDI-II (score <14; n = 370), the HADS-A, STAI and SSAI had moderate to high sensitivity (range from 50% to 80%) and specificity (range from 66% to 89%), and low PPVs (range from 2% to 11%) for GAD and any anxiety disorders. Here, GAD1 is linked to anxiety disorder.