Some AML subtypes showed specific immunophenotypic patterns of leukemic cells, such as coexpression of CD15, CD34 and sometimes, CD19 in AML with t(8;21); coexpression of CD13, CD33 in absence of CD34 and HLA-DR in AML with t(15;17) [4-6]; and coexpression of CD34, HLA-DR, CD15 and CD7 in AML with CEBPA mutation [7]. The gene discussed is ANPEP; the disease is acute myeloid leukemia.