Remarkbly, 19 out of 21 lipid genes (all except K12H4.5 and dhs-5; Table 3), are fairly conserved in humans and C. elegans. Moreover, C05D11.7, fat-6, dhs-16, fasn-1, pod-2, elo-3, and lpin-1 have relationships with human metabolic diseases. Here, LPIN1 is linked to Other metabolic disease.