GNRH1 and ovarian hyperstimulation syndrome: The same group of investigators subsequently reported that a dual trigger of final oocyte maturation with a GnRH agonist and low-dose hCG (1000 IU) resulted in improved implantation, clinical pregnancy, and live birth rates compared with a GnRH agonist alone, without increasing the risk of clinically significant OHSS in patients with peak estradiol levels <4000 pg/ml [91].