GNRH1 and Ovarian cyst: There are a number of theoretical advantages of GnRH antagonists versus GnRH agonists [12,13], including a shorter duration of injectable drug treatment, absence of vasomotor symptoms, less risk of inadvertent administration during early pregnancy, avoidance of ovarian cyst formation, and a significantly smaller dose of gonadotropin per cycle, which translate to improved patient convenience [9,14].