NOS1 and early-onset autosomal dominant Alzheimer disease: It is also possible that NOS-IR neurons are capable of better survival following oxaliplatin administration than other subgroups of myenteric neurons, as nNOS neurons have been shown to remain quite resistant to toxicities in Alzheimer's disease, Huntington's disease, and vascular stroke (Gonzalez-Zulueta et al., 1998).