IGHE and Increased total eosinophil count: As a consequence and/or origin of this cytokine secretion, there are alterations in leukocyte recruitment and activation, such as high levels of CD4+ T lymphocytes differentiated into Th2 and T regulatory (Treg) subsets, the recruitment and activation of immunoglobulin G1 (IgG1)- and IgE-producing B cells, eosinophilia, basophilia, and mastocytocis [4, 5].