CALCA and bacterial infectious disease: To obtain insight into the role of ST2 in the regulation of lung inflammation during postinfluenza pneumococcal pneumonia, we measured amphiregulin, cytokines (IFN-γ, TNFα, IL-1β, IL-6, IL-10, IL-33, IL-5, IL-13) and chemokines (KC, MIP-2) in lungs of mice 6, 24 and 48 hours after secondary bacterial infection (Figure 2).