CDH1 and neoplasm: In addition to 14-3-3ε positivity, expression of E-cadherin is significantly correlated with gender (p = 0.011), histology grade (p = 0.001), BCLC staging (p = 0.030), tumor size (p = 0.003), and subsequent extrahepatic metastasis (p = 0.004) (Table S3).